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gene-editing
2 free lessons tagged gene-editing across Science. Each one is a short sequence of focused steps with narration and a five-question quiz at the end — take them in any order, no signup required.
Science
intermediateBase editing and prime editing: precision without breaks
How base editors convert one base to another by chemistry rather than by cutting, how prime editors use a programmable template and reverse transcription to make arbitrary small edits, and the structural trade-offs between scope, efficiency, and off-target activity.
8 steps·~12 min
Science
intermediateCRISPR/Cas9: mechanism, repair, and delivery
How CRISPR/Cas9 cuts a specific DNA sequence using a programmable guide RNA, the two cellular repair pathways that determine whether the edit is a disruption or a correction, the structural problem of off-target effects, and what delivery into human cells actually requires.
8 steps·~12 min